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Treatment measures in rheumatology: An overview of the use of targeted biologic therapies

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Title: Treatment measures in rheumatology: An overview of the use of targeted biologic therapies Authors: Loughlin, Ciara Abstract: There have been many exciting developments in rheumatology over the last two decades. A greater understanding of the functioning of the immune system in rheumatologic disorders has resulted in the development of targeted biologic therapies for patients.1 Biologic therapies represent a new kind of treatment for patients with a wide range of rheumatologic conditions such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS) and systemic lupus erythematosus (SLE). Traditional therapies such as methotrexate, salazopyrine, plaquenil and arava are still very much part of the patients prescribed program with methotrexate remaining the first line treatment used in the management of inflammatory arthritis. However the advances in molecular biology have led to an array of new treatment approaches to inflammatory arthritis.2

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