Reply to Blot and to Inoue
McElvaney, Oliver J; McEvoy, Natalie L; McElvaney, Noel G; Curley, Gerard F
Reply to Blot et al. and to Inoue et al.
From the Authors:
We thank Blot and colleagues for their interest in our article and for
raising an important question regarding the suitability of IL-6 as
a therapeutic target in coronavirus disease (COVID-19).
In their correspondence, Blot and colleagues provide data on
IL-6 levels measured in patients with a diagnosis of COVID-19
versus non–COVID-19 pneumonia. Although we believe the
data presented by Blot and colleagues are valid, we suggest that the
IL-6 levels depicted are, by virtue of sample timing, processing
methodology, and patient severity of disease, not comparable to
ours and should be interpreted in context.
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